Ibuprofen administration attenuates serum TNF levels, hepatic glutathione depletion, hepatic apoptosis and mouse mortality after Fas stimulation ScienceDirect Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Does ibuprofen deplete glutathione? Did you know? Many commonly prescribed medications can quietly deplete your body of essential nutrients and most people are never told! From birth control to statins and acid blockers, these medications